Avène Tolérance Extrême : the sterile cosmetic for the most sensitive skins. The Avène Tolérance Extrême cares allow sensitive skins to be more focused on the essential. The Avène Tolérance Extrême range benefits from the Sterile Cosmetic technology. A technology that provides a unique safety for the most sensitive skins thanks to efficient and sure formula with a minimum of components, essential active ingredients, without preservative or equivalent. The Sterile Cosmetic is also a unique process of sterilization during the production and a patented closing system that avoids the contamination of formula by bacteria and that ensures to maintain sterility during the whole use.